side effect of leptospirosis vaccine in dogs

SIDE EFFECT OF LEPTOSPIROSIS VACCINE IN DOGS SERIES

Results suggested vaccination against Leptospira (an organism that can cause fatal disease) is safe in the majority of cases, slightly increasing the risk of owner-reported AEs but not associated with a significant increase in hypersensitivity reactions, compared with other vaccinations administered. Studies have shown similar rates for cats. That translates into roughly 38/10,000 (0.38 percent) of dogs having a vaccine reaction. Data varies, yet one major study found that in over 1 million vaccinated dogs, only 4,678 had a vaccine reaction.

The overall IR for owner-reported postvaccination AEs was low. Fever Vomiting Abdominal pain Diarrhea Refusal to eat Severe weakness and depression Stiffness Severe muscle pain Inability to have puppies. Vaccine reactions are relatively rare in pets. Hypersensitivity reactions were rare (IR, 6.5/10,000 dogs), and IRs for these events did not differ significantly between dogs vaccinated with or without a Leptospira component. Significant factors for increasing or decreasing risk of AEs were as follows: receiving a Leptospira vaccine (adjusted OR, 2.13), age at vaccination 1 to < 7 or ≥ 7 years (vs a referent of < 6 months adjusted OR, 0.54 and 0.44, respectively), and weight 13.6 to < 22.7 kg (30 to < 50 lb) and 22.7 to < 45.5 kg (50 to 100 lb adjusted OR, 0.48 and 0.55, respectively). The IR/10,000 dogs for owner-reported postvaccination AEs was 26.3 (95% CI, 23.6 to 29.2), whereas that for dogs that received a Leptospira vaccine alone or with other vaccines was 53.0 (95% CI, 42.8 to 64.9).

SIDE EFFECT OF LEPTOSPIROSIS VACCINE IN DOGS SERIES

This series of parvo vaccine for dogs will generally begin around 6 to 8 weeks of age and conclude around 4 months of age. In some dogs (Miniature Dachshunds and West Highland White Terriers. Vaccines have been shown to protect against serogroups in the vaccine for at least 6-8 months, and some report protection for 12 months. Your puppy will need to receive at least 3 to 4 doses of the parvo vaccine for the vaccine to be effective. As with any vaccine, it may cause lethargy for a few days and possible loss of appetite. Associations between potential risk factors and owner-reported AEs were evaluated by logistic regression analysis. Parvo is a fast-spreading deadly disease that can be prevented by giving your dog the canine parvovirus vaccine. Signalment data, vaccinations received, medications administered, and owner-reported clinical signs consistent with AEs that developed ≤ 5 days after vaccination were recorded. Observational, retrospective cohort study.Įlectronic records of mobile veterinary clinics from June 2012 to March 2013 were searched to identify dogs that received ≥ 1 vaccine in a given visit. To determine incidence rates (IRs) and potential risk factors for owner-reported adverse events (AEs) following vaccination of dogs that did or did not receive a Leptospira vaccine.

Side effect of leptospirosis vaccine in dogs